Recombinant Human HERC3 cell lysate

• Cat.No.: HERC3-780HCL

Specification

• Description: HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 [ Homo sapiens ]
• Official Symbol: HERC3
• Synonyms: HERC3; HECT and RLD domain containing E3 ubiquitin protein ligase 3; hect domain and RLD 3; probable E3 ubiquitin-protein ligase HERC3; KIAA0032; HECT domain and RCC1-like domain-containing protein 3
• Gene ID: 8916
• mRNA Refseq: NM_014606
• Protein Refseq: NP_055421
• MIM: 605200
• UniProt ID: Q15034
• Chromosome Location: 4q21
• Pathway: Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem
• Function: acid-amino acid ligase activity; ligase activity; ubiquitin-protein ligase activity