Recombinant Human HTR3B cell lysate

• Cat.No.: HTR3B-828HCL

Specification

• Description: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic [ Homo sapiens ]
• Official Symbol: HTR3B
• Synonyms: HTR3B; 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic; 5 hydroxytryptamine (serotonin) receptor 3B; 5-hydroxytryptamine receptor 3B; 5 HT3B; 5-HT3-B; serotonin-gated ion channel subunit; 5-hydroxytryptamine 3 receptor B subunit; 5-HT3B
• Gene ID: 9177
• mRNA Refseq: NM_006028
• Protein Refseq: NP_006019
• MIM: 604654
• UniProt ID: O95264
• Chromosome Location: 11q23.1
• Pathway: Ion channel transport, organism-specific biosystem; Ligand-gated ion channel transport, organism-specific biosystem; Serotonergic synapse, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem
• Function: extracellular ligand-gated ion channel activity; ion channel activity; receptor activity; serotonin receptor activity; serotonin-activated cation-selective channel activity