Recombinant Human ITPKB cell lysate

• Cat.No.: ITPKB-883HCL

Specification

• Description: The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: ITPKB inositol-trisphosphate 3-kinase B [ Homo sapiens ]
• Official Symbol: ITPKB
• Synonyms: ITPKB; inositol-trisphosphate 3-kinase B; inositol 1,4,5 trisphosphate 3 kinase B; IP3 3KB; IP3KB; IP3K B; IP3 3-kinase B; insP 3-kinase B; proliferation-inducing protein 37; inositol 1,4,5-trisphosphate 3-kinase B; IP3K; PIG37; IP3K-B; IP3-3KB
• Gene ID: 3707
• mRNA Refseq: NM_002221
• Protein Refseq: NP_002212
• MIM: 147522
• UniProt ID: P27987
• Chromosome Location: 1q42.12
• Pathway: 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian), organism-specific biosystem; 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian), conserved biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; D-myo-inositol (1,3,4)-trisphosphate biosynthesis, organism-specific biosystem; D-myo-inositol (1,3,4)-trisphosphate biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem
• Function: ATP binding; calmodulin binding; inositol-1,4,5-trisphosphate 3-kinase activity; kinase activity; nucleotide binding; transferase activity