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Recombinant Human LMNB1 cell lysate

Cat.No.: LMNB1-994HCL
Description: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: LMNB1 lamin B1 [ Homo sapiens ]
Official Symbol: LMNB1
Synonyms: LMNB1; lamin B1; lamin-B1; LMN; ADLD; LMN2; LMNB; MGC111419;
Gene ID: 4001
mRNA Refseq: NM_001198557
Protein Refseq: NP_001185486
MIM: 150340
UniProt ID: P20700
Chromosome Location: 5q23.2
Pathway: Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Breakdown of the nuclear lamina, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem;
Function: phospholipase binding; structural molecule activity;

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