Recombinant Human LMNB1 cell lysate

• Cat.No.: LMNB1-994HCL

Specification

• Description: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: LMNB1 lamin B1 [ Homo sapiens ]
• Official Symbol: LMNB1
• Synonyms: LMNB1; lamin B1; lamin-B1; LMN; ADLD; LMN2; LMNB; MGC111419
• Gene ID: 4001
• mRNA Refseq: NM_001198557
• Protein Refseq: NP_001185486
• MIM: 150340
• UniProt ID: P20700
• Chromosome Location: 5q23.2
• Pathway: Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Breakdown of the nuclear lamina, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem
• Function: phospholipase binding; structural molecule activity