Recombinant Human MXD4 cell lysate
- Specification
- Gene Information
- Related Products
| Description : |
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. |
| Species : |
Human |
| Size : |
100 ul |
| Storage Buffer : |
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
| Applications : |
Western Blot; |
| Gene Name : |
MXD4 MAX dimerization protein 4 [ Homo sapiens ] |
| Official Symbol : |
MXD4 |
| Synonyms : |
MXD4; MAX dimerization protein 4; max dimerization protein 4; bHLHc12; MAD4; MST149; MSTP149; Mad4 homolog; max dimerizer 4; max-associated protein 4; class C basic helix-loop-helix protein 12; max-interacting transcriptional repressor MAD4; |
| Gene ID : |
10608 |
| mRNA Refseq : |
NM_006454 |
| Protein Refseq : |
NP_006445 |
| UniProt ID : |
Q14582 |
| Chromosome Location : |
4p16.3 |
| Pathway : |
Validated targets of C-MYC transcriptional repression, organism-specific biosystem; |
| Function : |
DNA binding; transcription corepressor activity; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
