"MXD4" Related Products


Recombinant Human MXD4 cell lysate

Cat.No.: MXD4-1157HCL
Description: This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: MXD4 MAX dimerization protein 4 [ Homo sapiens ]
Official Symbol: MXD4
Synonyms: MXD4; MAX dimerization protein 4; max dimerization protein 4; bHLHc12; MAD4; MST149; MSTP149; Mad4 homolog; max dimerizer 4; max-associated protein 4; class C basic helix-loop-helix protein 12; max-interacting transcriptional repressor MAD4;
Gene ID: 10608
mRNA Refseq: NM_006454
Protein Refseq: NP_006445
UniProt ID: Q14582
Chromosome Location: 4p16.3
Pathway: Validated targets of C-MYC transcriptional repression, organism-specific biosystem;
Function: DNA binding; transcription corepressor activity;

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