Recombinant Human NCBP1 cell lysate

• Cat.No.: NCBP1-1171HCL

Specification

• Description: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5 cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: NCBP1 nuclear cap binding protein subunit 1, 80kDa [ Homo sapiens ]
• Official Symbol: NCBP1
• Synonyms: NCBP1; nuclear cap binding protein subunit 1, 80kDa; NCBP, nuclear cap binding protein subunit 1, 80kD; nuclear cap-binding protein subunit 1; CBP80; Sto1; NCBP 80 kDa subunit; 80 kDa nuclear cap-binding protein; NCBP; MGC2087
• Gene ID: 4686
• mRNA Refseq: NM_002486
• Protein Refseq: NP_002477
• MIM: 600469
• UniProt ID: Q09161
• Chromosome Location: 9q34.1
• Pathway: Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Cap binding complex, organism-specific biosystem; Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem; Disease, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem
• Function: RNA binding; RNA cap binding; protein binding