Recombinant Human OAZ3 cell lysate

• Cat.No.: OAZ3-1243HCL

Specification

• Description: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: OAZ3?ornithine decarboxylase antizyme 3 [?Homo sapiens?(human) ]
• Official Symbol: OAZ3
• Synonyms: OAZ3; ornithine decarboxylase antizyme 3; AZ3; OAZ-t; TISP15; ornithine decarboxylase antizyme 3; ODC-Az 3; antizyme 3
• Gene ID: 51686
• mRNA Refseq: NM_001134939
• Protein Refseq: NP_001128411
• MIM: 605138
• UniProt ID: Q9UMX2
• Chromosome Location: 1q21.3
• Pathway: Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Regulation of ornithine decarboxylase (ODC), organism-specific biosystem
• Function: ankyrin repeat binding; ornithine decarboxylase inhibitor activity; protein binding