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Recombinant Human OAZ3 cell lysate

Cat.No.: OAZ3-1243HCL
Description: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: OAZ3?ornithine decarboxylase antizyme 3 [?Homo sapiens?(human) ]
Official Symbol: OAZ3
Synonyms: OAZ3; ornithine decarboxylase antizyme 3; AZ3; OAZ-t; TISP15; ornithine decarboxylase antizyme 3; ODC-Az 3; antizyme 3
Gene ID: 51686
mRNA Refseq: NM_001134939
Protein Refseq: NP_001128411
MIM: 605138
UniProt ID: Q9UMX2
Chromosome Location: 1q21.3
Pathway: Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Regulation of ornithine decarboxylase (ODC), organism-specific biosystem
Function: ankyrin repeat binding; ornithine decarboxylase inhibitor activity; protein binding

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