Recombinant Human PANK1 cell lysate

• Cat.No.: PANK1-1278HCL

Specification

• Description: This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PANK1 pantothenate kinase 1 [ Homo sapiens ]
• Official Symbol: PANK1
• Synonyms: PANK1; pantothenate kinase 1; PANK, pantothenate kinase; MGC24596; PANK1a; PANK1b; pantothenic acid kinase 1; PANK
• Gene ID: 53354
• mRNA Refseq: NM_138316
• Protein Refseq: NP_612189
• MIM: 606160
• UniProt ID: Q8TE04
• Chromosome Location: 10q23.31
• Pathway: Coenzyme A biosynthesis, organism-specific biosystem; Coenzyme A biosynthesis, pantothenate =>CoA, organism-specific biosystem; Coenzyme A biosynthesis, pantothenate => CoA, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem
• Function: ATP binding; nucleotide binding; pantothenate kinase activity; transferase activity