Recombinant Human PARD3 cell lysate

• Cat.No.: PARD3-1283HCL

Specification

• Description: PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PARD3 par-3 partitioning defective 3 homolog (C. elegans) [ Homo sapiens ]
• Official Symbol: PARD3
• Synonyms: PARD3; par-3 partitioning defective 3 homolog (C. elegans); par 3 (partitioning defective 3, C.elegans) homolog; partitioning defective 3 homolog; ASIP; atypical PKC isotype specific interacting protein; Baz; Bazooka; PAR3; PARD3A; PARD-3; PAR3-alpha; CTCL tumor antigen se2-5; atypical PKC isotype-specific interacting protein; atypical PKC isotype-specific-interacting protein; SE2-5T2; SE2-5L16; SE2-5LT1; PAR3alpha; FLJ21015
• Gene ID: 56288
• mRNA Refseq: NM_001184785
• Protein Refseq: NP_001171714
• MIM: 606745
• UniProt ID: Q8TEW0
• Chromosome Location: 10p11.22
• Pathway: Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem
• Function: lipid binding; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; protein kinase C binding