Recombinant Human PCDHB2 cell lysate

• Cat.No.: PCDHB2-1299HCL

Specification

• Description: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3 exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PCDHB2 protocadherin beta 2 [ Homo sapiens ]
• Official Symbol: PCDHB2
• Synonyms: PCDHB2; protocadherin beta 2; protocadherin beta-2; PCDH BETA2; PCDH-beta-2; PCDH-BETA2; MGC111392
• Gene ID: 56133
• mRNA Refseq: NM_018936
• Protein Refseq: NP_061759
• MIM: 606328
• UniProt ID: Q9Y5E7
• Chromosome Location: 5q31
• Function: calcium ion binding