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Recombinant Human PCDHGA12 cell lysate

Cat.No. : PCDHGA12-1303HCL
  • Specification
  • Gene Information
  • Related Products
Description : This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : PCDHGA12 protocadherin gamma subfamily A, 12 [ Homo sapiens ]
Official Symbol : PCDHGA12
Synonyms : PCDHGA12; protocadherin gamma subfamily A, 12; cadherin 21 , CDH21; protocadherin gamma-A12; FIB3; fibroblast cadherin FIB3; KIAA0588; PCDH GAMMA A12; cadherin 21; cadherin-21; fibroblast cadherin-3; CDH21; PCDH-GAMMA-A12;
Gene ID : 26025
mRNA Refseq : NM_003735
Protein Refseq : NP_003726
MIM : 603059
UniProt ID : O60330
Chromosome Location : 5q31
Function : calcium ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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