"PCDHGA12" Related Products

Recombinant Human PCDHGA12 cell lysate

Cat.No.: PCDHGA12-1303HCL
Description: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: PCDHGA12 protocadherin gamma subfamily A, 12 [ Homo sapiens ]
Official Symbol: PCDHGA12
Synonyms: PCDHGA12; protocadherin gamma subfamily A, 12; cadherin 21 , CDH21; protocadherin gamma-A12; FIB3; fibroblast cadherin FIB3; KIAA0588; PCDH GAMMA A12; cadherin 21; cadherin-21; fibroblast cadherin-3; CDH21; PCDH-GAMMA-A12;
Gene ID: 26025
mRNA Refseq: NM_003735
Protein Refseq: NP_003726
MIM: 603059
UniProt ID: O60330
Chromosome Location: 5q31
Function: calcium ion binding;

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