"PCDHGA8" Related Products

Recombinant Human PCDHGA8 cell lysate

Cat.No.: PCDHGA8-1305HCL
Description: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: PCDHGA8 protocadherin gamma subfamily A, 8 [ Homo sapiens ]
Official Symbol: PCDHGA8
Synonyms: PCDHGA8; protocadherin gamma subfamily A, 8; protocadherin gamma-A8; KIAA0327; PCDH GAMMA A8; PCDH-GAMMA-A8;
Gene ID: 9708
mRNA Refseq: NM_014004
Protein Refseq: NP_054723
MIM: 606295
UniProt ID: Q9Y5G5
Chromosome Location: 5q31
Function: calcium ion binding;

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