Recombinant Human PCLO cell lysate

• Cat.No.: PCLO-1311HCL

Specification

• Description: Synaptic vesicles dock and fuse in the active zone of the plasma membrane at chemical synapses. The presynaptic cytoskeletal matrix (PCM), which is associated with the active zone and is situated between synaptic vesicles, is thought to be involved in maintaining the neurotransmitter release site in register with the postsynaptic reception apparatus. The cycling of synaptic vesicles is a multistep process involving a number of proteins (see MIM 603215). Among the components of the PCM that orchestrate these events are Bassoon (BSN; MIM 604020), RIM (RBBP8; MIM 604124), Oboe, and Piccolo (PCLO).
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PCLO piccolo (presynaptic cytomatrix protein) [ Homo sapiens ]
• Official Symbol: PCLO
• Synonyms: PCLO; piccolo (presynaptic cytomatrix protein); protein piccolo; ACZ; aczonin; DKFZp779G1236; KIAA0559
• Gene ID: 27445
• mRNA Refseq: NM_014510
• Protein Refseq: NP_055325
• MIM: 604918
• UniProt ID: Q9Y6V0
• Chromosome Location: 7q11.23-q21.3
• Function: calcium ion binding; calcium-dependent phospholipid binding; profilin binding; transporter activity