Recombinant Human RNASEH2A cell lysate
Cat.No. : | RNASEH2A-1515HCL |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | RNASEH2A ribonuclease H2, subunit A [ Homo sapiens ] |
Official Symbol : | RNASEH2A |
Synonyms : | RNASEH2A; ribonuclease H2, subunit A; Aicardi Goutieres syndrome 4 , ribonuclease H2, large subunit; ribonuclease H2 subunit A; AGS4; RNASEHI; RNHIA; RNHL; RNase H(35); RNase H2 subunit A; RNase HI large subunit; ribonuclease HI subunit A; ribonuclease HI large subunit; ribonuclease H2, large subunit; ribonuclease HI, large subunit; aicardi-Goutieres syndrome 4 protein; JUNB; |
Gene ID : | 10535 |
mRNA Refseq : | NM_006397 |
Protein Refseq : | NP_006388 |
MIM : | 606034 |
UniProt ID : | O75792 |
Chromosome Location : | 19p13.13 |
Pathway : | DNA replication, organism-specific biosystem; DNA replication, conserved biosystem; |
Function : | RNA binding; endonuclease activity; hydrolase activity; metal ion binding; ribonuclease H activity; ribonuclease activity; |
Products Types
◆ Recombinant Protein | ||
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RNASEH2A-1257H | Recombinant Human RNASEH2A Protein, MYC/DDK-tagged | +Inquiry |
Rnaseh2a-5537M | Recombinant Mouse Rnaseh2a Protein, Myc/DDK-tagged | +Inquiry |
RNASEH2A-10566Z | Recombinant Zebrafish RNASEH2A | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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