Recombinant Human SLC6A4 cell lysate
Cat.No. : | SLC6A4-1638HCL |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | SLC6A4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 [ Homo sapiens ] |
Official Symbol : | SLC6A4 |
Synonyms : | SLC6A4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; HTT; sodium-dependent serotonin transporter; 5 HTT; SERT1; 5HT transporter; 5-hydroxytryptamine transporter; solute carrier family 6 member 4; Na+/Cl- dependent serotonin transporter; 5HTT; OCD1; SERT; 5-HTT; hSERT; 5-HTTLPR; |
Gene ID : | 6532 |
mRNA Refseq : | NM_001045 |
Protein Refseq : | NP_001036 |
MIM : | 182138 |
UniProt ID : | P31645 |
Chromosome Location : | 17q11.2 |
Pathway : | Monoamine Transport, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem; Serotonergic synapse, organism-specific biosystem; |
Function : | Rab GTPase binding; actin filament binding; cocaine binding; monoamine transmembrane transporter activity; myosin binding; nitric-oxide synthase binding; protein binding; protein homodimerization activity; serotonin transmembrane transporter activity; serotonin transmembrane transporter activity; serotonin:sodium symporter activity; serotonin:sodium symporter activity; symporter activity; syntaxin-1 binding; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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