"SNX15" Related Products

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Recombinant Human SNX15 cell lysate

Cat.No.: SNX15-1660HCL
Description: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: SNX15 sorting nexin 15 [ Homo sapiens ]
Official Symbol: SNX15
Synonyms: SNX15; sorting nexin 15; sorting nexin-15; clone iota unknown protein; HSAF001435;
Gene ID: 29907
mRNA Refseq: NM_013306
Protein Refseq: NP_037438
MIM: 605964
UniProt ID: Q9NRS6
Chromosome Location: 11q12
Pathway: PDGFR-beta signaling pathway, organism-specific biosystem;
Function: lipid binding; phosphatidylinositol binding; protein transporter activity;

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