Recombinant Human SOAT1 cell lysate

• Cat.No.: SOAT1-1665HCL

Specification

• Species: Human
• Tag: Non
• Description: Acyl-coenzyme A:cholesterol acyltransferase (ACACT; EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988 [PubMed 3335499]).
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: SOAT1 sterol O-acyltransferase 1 [ Homo sapiens ]
• Official Symbol: SOAT1
• Synonyms: SOAT1; sterol O-acyltransferase 1; SOAT, STAT, sterol O acyltransferase (acyl Coenzyme A: cholesterol acyltransferase) 1; ACAT; acyl Coenzyme A: cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase 1; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; SOAT; STAT; ACACT; ACAT1; ACAT-1
• Gene ID: 6646
• mRNA Refseq: NM_001252511
• Protein Refseq: NP_001239440
• MIM: 102642
• UniProt ID: P35610
• Chromosome Location: 1q25
• Pathway: Statin Pathway, organism-specific biosystem; Steroid biosynthesis, organism-specific biosystem; Steroid biosynthesis, conserved biosystem
• Function: cholesterol O-acyltransferase activity; cholesterol O-acyltransferase activity; cholesterol binding; fatty-acyl-CoA binding; sterol O-acyltransferase activity; sterol O-acyltransferase activity; transferase activity, transferring acyl groups