Recombinant Human SORCS3 cell lysate

• Cat.No.: SORCS3-1670HCL

Specification

• Description: This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: SORCS3 sortilin-related VPS10 domain containing receptor 3 [ Homo sapiens ]
• Official Symbol: SORCS3
• Synonyms: SORCS3; sortilin-related VPS10 domain containing receptor 3; VPS10 domain-containing receptor SorCS3; KIAA1059; SORCS; 6330404A12Rik; VPS10 domain receptor protein SORCS 3 (SORCS3); RP11-107L7.1
• Gene ID: 22986
• mRNA Refseq: NM_014978
• Protein Refseq: NP_055793
• MIM: 606285
• UniProt ID: Q9UPU3
• Chromosome Location: 10q23-q25
• Pathway: NFG and proNGF binds to p75NTR, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signalling by NGF, organism-specific biosystem; p75 NTR receptor-mediated signalling, organism-specific biosystem
• Function: neuropeptide receptor activity