Recombinant Human SOX12 cell lysate

• Cat.No.: SOX12-1671HCL

Specification

• Description: Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: SOX12 SRY (sex determining region Y)-box 12 [ Homo sapiens ]
• Official Symbol: SOX12
• Synonyms: SOX12; SRY (sex determining region Y)-box 12; SOX22, SRY (sex determining region Y) box 22; transcription factor SOX-12; SOX-22 protein; SRY-related HMG-box gene 22; SRY (sex determining region Y)-box 22; SOX22
• Gene ID: 6666
• mRNA Refseq: NM_006943
• Protein Refseq: NP_008874
• MIM: 601947
• UniProt ID: O15370
• Chromosome Location: 20p13
• Function: DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription coactivator activity; transcription regulatory region sequence-specific DNA binding