"TIA1" Related Products

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Recombinant Human TIA1 cell lysate

Cat.No.: TIA1-1778HCL
Description: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: TIA1 TIA1 cytotoxic granule-associated RNA binding protein [ Homo sapiens ]
Official Symbol: TIA1
Synonyms: TIA1; TIA1 cytotoxic granule-associated RNA binding protein; TIA1 cytotoxic granule associated RNA binding protein; nucleolysin TIA-1 isoform p40; nucleolysin TIA 1 isoform p40; T cell restricted intracellular antigen 1; p40-TIA-1 (containing p15-TIA-1); T-cell-restricted intracellular antigen-1; TIA-1;
Gene ID: 7072
mRNA Refseq: NM_022037
Protein Refseq: NP_071320
MIM: 603518
UniProt ID: P31483
Chromosome Location: 2p13
Function: AU-rich element binding; nucleic acid binding; nucleotide binding; poly(A) RNA binding; protein binding;

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