Recombinant Human TRIM23 cell lysate

• Cat.No.: TRIM23-1824HCL

Specification

• Description: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: TRIM23 tripartite motif containing 23 [ Homo sapiens ]
• Official Symbol: TRIM23
• Synonyms: TRIM23; tripartite motif containing 23; ADP ribosylation factor domain protein 1, 64kDa , ARFD1, tripartite motif containing 23; E3 ubiquitin-protein ligase TRIM23; ARD1; RNF46; ARF domain protein 1; RING finger protein 46; GTP-binding protein ARD-1; tripartite motif-containing 23; tripartite motif protein TRIM23; tripartite motif-containing protein 23; ADP-ribosylation factor domain protein 1, 64kDa; ADP-ribosylation factor domain-containing protein 1; ARFD1
• Gene ID: 373
• mRNA Refseq: NM_001656
• Protein Refseq: NP_001647
• MIM: 601747
• UniProt ID: P36406
• Chromosome Location: 5q12.3
• Function: GDP binding; GTP binding; GTPase activity; enzyme activator activity; ligase activity; metal ion binding; nucleotide binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding