Recombinant Human TSEN2 cell lysate

• Cat.No.: TSEN2-1843HCL

Specification

• Description: This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: TSEN2 tRNA splicing endonuclease 2 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: TSEN2
• Synonyms: TSEN2; tRNA splicing endonuclease 2 homolog (S. cerevisiae); tRNA splicing endonuclease 2 homolog (SEN2, S. cerevisiae); tRNA-splicing endonuclease subunit Sen2; MGC2776; SEN2; SEN2L; hsSen2; tRNA-intron endonuclease Sen2; PCH2B; MGC4440
• Gene ID: 80746
• mRNA Refseq: NM_001145392
• Protein Refseq: NP_001138864
• MIM: 608753
• UniProt ID: Q8NCE0
• Chromosome Location: 3p25.2
• Function: endonuclease activity; hydrolase activity; nucleic acid binding; tRNA-intron endonuclease activity