"UBR2" Related Products

Recombinant Human UBR2 cell lysate

Cat.No.: UBR2-1876HCL
Description: Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrates destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: UBR2 ubiquitin protein ligase E3 component n-recognin 2 [ Homo sapiens ]
Official Symbol: UBR2
Synonyms: UBR2; ubiquitin protein ligase E3 component n-recognin 2; C6orf133, chromosome 6 open reading frame 133; E3 ubiquitin-protein ligase UBR2; bA49A4.1; dJ392M17.3; KIAA0349; ubiquitin-protein ligase E3-alpha-2; ubiquitin-protein ligase E3-alpha-II; C6orf133; dJ242G1.1; RP3-392M17.3; FLJ36357; MGC71112; DKFZp686C08114;
Gene ID: 23304
mRNA Refseq: NM_001184801
Protein Refseq: NP_001171730
MIM: 609134
UniProt ID: Q8IWV8
Chromosome Location: 6p21.1
Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem;
Function: leucine binding; ligase activity; metal ion binding; ubiquitin-protein ligase activity; zinc ion binding;
Products Types ◆ Recombinant Protein

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