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Recombinant Human WHSC2 cell lysate

Cat.No. : WHSC2-1932HCL
  • Specification
  • Gene Information
  • Related Products
Description : This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : WHSC2 Wolf-Hirschhorn syndrome candidate 2 [ Homo sapiens ]
Official Symbol : WHSC2
Synonyms : WHSC2; Wolf-Hirschhorn syndrome candidate 2; negative elongation factor A; NELF A; wolf-Hirschhorn syndrome candidate 2 protein; NELFA; NELF-A; P/OKcl.15; FLJ10442; FLJ25112;
Gene ID : 7469
mRNA Refseq : NM_005663
Protein Refseq : NP_005654
MIM : 606026
UniProt ID : Q9H3P2
Chromosome Location : 4p16.3
Pathway : Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Disease, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem; Formation of the Early Elongation Complex, organism-specific biosystem; Formation of the HIV-1 Early Elongation Complex, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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