Recombinant Human YAF2 cell lysate

• Cat.No.: YAF2-1943HCL

Specification

• Description: The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: YAF2 YY1 associated factor 2 [ Homo sapiens ]
• Official Symbol: YAF2
• Synonyms: YAF2; YY1 associated factor 2; YY1-associated factor 2; MGC41856; DKFZp779H1820
• Gene ID: 10138
• mRNA Refseq: NM_001190977
• Protein Refseq: NP_001177906
• MIM: 607534
• UniProt ID: Q8IY57
• Chromosome Location: 12q12
• Function: metal ion binding; protein binding; transcription coactivator activity; transcription corepressor activity; zinc ion binding