| Cat.No.: | HCV-1a E2-30H |
| Product Overview: | A DNA sequence encoding the Hepatitis C virus (serotype 1a, isolate H77) E2 protein (NP_751921.1) (Glu1-Glu278) was expressed with a polyhistidine tag at the C-terminus. |
| Description: | E2 is a viral structural protein found in the hepatitis C virus. It is present on the viral membrane and functions as a host receptor binding protein, mediating entry into host cells. Therefore, it is a key target for the design of entry inhibitors and vaccine immunogens. Hepatitis C virus (HCV or sometimes HVC) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. Hepatitis C virus is the cause of hepatitis C in humans. |
| Source: | Human Cells |
| Species: | HCV |
| Tag: | His |
| Predicted N Terminal: | Glu |
| Form: | Lyophilized from sterile PBS, pH 7.41. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.2. Please contact us for any concerns or special requirements. |
| Molecular Mass: | The recombinant virus E2 consists 289 amino acids and predicts a molecular mass of 32 kDa. |
| Endotoxin: | < 1.0 eu per μg of the protein as determined by the lal |
| Purity: | >95 % as determined by SDS-PAGE |
| Storage: | Store it under sterile conditions at -20? to -80?. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Reconstitution: | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
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