"ROR2" Related Products

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Recombinant Human ROR2, Fc-tagged

Cat.No.: ROR2-183H
Product Overview: Recombinant Human ROR2 /NTRKR2 Protein, With C-Fc Tag (rh ROR2 Fc Chimera) Val 34 - Gly 403 (Accession # NP_004551) was produced in human 293 cells (HEK293).
Description: Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.
Source: HEK293
Species: Human
Tag: Fc
Form: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM NaCl, pH 7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass: rh ROR2 Fc Chimera is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 67.9 kDa. The predicted N-terminus is Val 34. DTT-reduced Protein migrates as 80-90 kDa in SDS-PAGE due to glycosylation.
Endotoxin: Less than 1.0 EU per μg of the rh ROR2 Fc Chimera by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC).
Reconstitution: See Certificate of Analysis for reconstitution instructions and specific concentrations.
Gene Name: ROR2 receptor tyrosine kinase-like orphan receptor 2 [ Homo sapiens ]
Official Symbol: ROR2
Synonyms: ROR2; receptor tyrosine kinase-like orphan receptor 2; BDB, BDB1, NTRKR2; tyrosine-protein kinase transmembrane receptor ROR2; neurotrophic tyrosine kinase receptor-related 2; BDB; BDB1; NTRKR2; MGC163394;
Gene ID: 4920
mRNA Refseq: NM_004560
Protein Refseq: NP_004551
MIM: 602337
UniProt ID: Q01974
Chromosome Location: 9q22
Pathway: Noncanonical Wnt signaling pathway, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt signaling network, organism-specific biosystem;
Function: ATP binding; Wnt-protein binding; frizzled binding; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity;

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