Recombinant Human PDE10A, GST-tagged

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Recombinant Human PDE10A, GST-tagged

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Cat.No. : PDE10A-1610H
Product Overview : Recombinant human PDE10A (71-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.?
Source : Sf9 insect cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 92 nmol/min/mg
Molecular Mass : ~102 kDa
Protein length : 71-end
Purity : >80%
Applications : PDE Assay
Stability : 1 yr at -70oC from date of shipment.
Storage : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 ug/ul
Gene Name : PDE10A phosphodiesterase 10A [ Homo sapiens ]
Official Symbol : PDE10A
Synonyms : PDE10A; phosphodiesterase 10A; FLJ11894; FLJ25677; HSPDE10A; OTTHUMP00000017586; phosphodiesterase 10A1 (PDE10A1); dJ416F21.1 (phosphodiesterase 10A); EC 3.1.4.17; EC 3.1.4.35
Gene ID : 10846
mRNA Refseq : NM_001130690
Protein Refseq : NP_001124162
MIM : 610652
UniProt ID : Q9Y233
Chromosome Location : 6q26
Pathway : G alpha (s) signalling events; Purine metabolism; Signaling by GPCR
Function : 3",5"-cyclic-GMP phosphodiesterase activity; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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