"PON1" Related Products

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Recombinant Human PON1, His-tagged

Cat.No. : PON1-06H
Product Overview : Recombinant full length human PON1 was produced from the synthetic gene with the C-terminal 6xHis tag in Trichoplusia ni larval expression system.
Description : PON1 hydrolyzes the toxic metabolites of a broad spectrum of organophosphate substrates. PON1 mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Source : Trichoplusia ni larval expression system
Species : Human
Tag : His
Form : 1 mg/mL in 50 mM Tris, 200 mM NaCl, 2 mM CaCl2, 0.2 μm filtered.
AA Sequence : MAKLIALTLL GMGLALFRNH QSSYQTRLNA LREVQPVELP NCNLVKGIET GSEDMEILPN GLAFISSGLK YPGIKSFNPN SPGKILLMDL NEEDPTVLEL GITGSKFDVS SFNPHGISTFTDEDNAMYLL VVNHPDAKST VELFKFQEEE KSLLHLKTIR HKLLPNLNDI VAVGPEHFYG TNDHYFLDPY LQSWEMYLGL AWSYVVYYSP SEVRVVAEGF DFANGINISP DGKYVYIAELLAHKIHVYEK HANWTLTPLK SLDFNTLVDN ISVDPETGDL WVGCHPNGMK IFFYDSENPP ASEVLRIQNI LTEEPKVTQV YAENGTVLQG STVASVYKGK LLIGTVFHKA LYCELHHHHHH
Purity : >90% as determined by SDS-PAGE
Storage : Store at -80°C or colder upon arrival. Freeze-thaw cycles of this product should be avoided.
Gene Name : PON1 paraoxonase 1 [ Homo sapiens ]
Official Symbol : PON1
Synonyms : ESA; PON; MVCD5; serum paraoxonase/arylesterase 1; K-45; PON 1; esterase A; A-esterase 1; arylesterase 1; paraoxonase B-type; aromatic esterase 1; arylesterase B-type; serum aryldiakylphosphatase; serum aryldialkylphosphatase 1
Gene ID : 5444
mRNA Refseq : NM_000446
Protein Refseq : NP_000437
MIM : 168820
UniProt ID : P27169
Chromosome Location : 7q21.3
Pathway : Metabolic pathways, organism-specific biosystem; Phase I, non P450, organism-specific biosystem
Function : aryldialkylphosphatase activity; arylesterase activity; calcium ion binding

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