Active Recombinant Human PADI4, Flag-tagged

• Cat.No.: PADI4-20H
• Product Overview: Human PADI-4, also known as Peptidyl arginine deiminase, type IV, 1-663(end), with C-terminal FLAG-tag, MW= 75 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Specification

• Description: This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.
• Source: Sf9 insect cells
• Species: Human
• Tag: Flag
• Form: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 80 µg/ml FLAG peptide
• Bio-activity: ≥80 pmole/min/µg
• Molecular Mass: 75 kDa
• Purity: ≥65%
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Storage: >6 months at –80°C.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: PADI4 peptidyl arginine deiminase, type IV [ Homo sapiens ]
• Official Symbol: PADI4
• Synonyms: PADI4; peptidyl arginine deiminase, type IV; PAD; PAD4; PDI4; PDI5; PADI5; protein-arginine deiminase type-4; HL-60 PAD; PADI-H protein; OTTHUMP00000002482; protein-arginine deiminase type IV; peptidyl arginine deiminase, type V
• Gene ID: 23569
• mRNA Refseq: NM_012387
• Protein Refseq: NP_036519
• MIM: 605347
• UniProt ID: Q9UM07
• Chromosome Location: 1p36.13
• Pathway: protein citrullination
• Function: arginine deiminase activity; calcium ion binding; protein binding; protein-arginine deiminase activity