"TSHB" Related Products

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Recombinant Human Thyroid Stimulating Hormone Beta

Cat.No.: TSHB-51H
Product Overview: Recombinant Human Thyroid Stimulating Hormone Beta was expressed in yeast.
Description: Thyrotropin-stimulating hormone (TSH) is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit (TSHA) and a unique beta subunit that confers specificity.Using bovine TSHB cDNA as probe, Hayashizaki et al. (1985) cloned TSHB from human liver and leukocyte genomic DNA libraries. Human TSHB encodes a deduced protein consisting of a 20-amino acid signal sequence, a mature protein of 112 amino acids, and a C-terminal extension of 6 hydrophobic amino acids. Wondisford et al. (1988) also cloned the human TSHB gene.Wondisford et al. (1988) determined that the TSHB gene contains 3 exons, the first of which is noncoding. The rat TSHB gene also contains one 5-prime noncoding exon, whereas the mouse Tshb gene contains 3.
Source: Yeast
Species: Human
Form: Lyophilized from sterile 20mM PB,240mM NaCl,PH6.0.
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: >95 % as determined by SDS-PAGE
Applications: Western blotting, ELISA
Storage: Store it under sterile conditions at -20℃ to -101℃ upon receiving.Recommend to aliquot the protein into smaller quantities for optimal storage.
Gene Name: TSHB thyroid stimulating hormone, beta [ Homo sapiens ]
Official Symbol: TSHB
Synonyms: TSHB; thyroid stimulating hormone, beta; thyrotropin subunit beta; thyrotropin beta chain; thyrotropin beta subunit; thyroid-stimulating hormone subunit beta; TSH-B; TSH-BETA;
Gene ID: 7252
mRNA Refseq: NM_000549
Protein Refseq: NP_000540
MIM: 188540
UniProt ID: P01222
Chromosome Location: 1p13
Pathway: Amine-derived hormones, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
Function: hormone activity;

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