Recombinant Human PRDM10, FLAG-tagged

• Cat.No.: PRDM10-65H
• Product Overview: Recombinant Human PRDM10 (accession number NP_064613.2) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 134 kDa.

Specification

• Description: PRDM10 (PR Domain Containing 10) is a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. PRDM10 is a transcription factor that contains C2H2-type zinc-fingers and that possesses histone methyltransferase activity. PRDM10 also contains a positive regulatory domain which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
• Source: Sf9 insect cells
• Species: Human
• Tag: FLAG
• Form: 25 mM HEPES, pH 7.5, 150 mM NaCl and 5% glycerol.
• Applications: Enzyme kinetics, inhibitor screening, and selectivity profiling.
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
• Concentration: 0.4 mg/ml

Gene Information

• Gene Name: PRDM10 PR domain containing 10 [ Homo sapiens ]
• Official Symbol: PRDM10
• Synonyms: PRDM10; PR domain containing 10; PR domain zinc finger protein 10; KIAA1231; MGC131802; PFM7; PR domain family member 7; PRDM zinc finger transcription factor; tristanin; PR-domain family member 7; PR domain-containing protein 10
• Gene ID: 56980
• mRNA Refseq: NM_020228
• Protein Refseq: NP_064613
• UniProt ID: Q9NQV6
• Chromosome Location: 11q25
• Function: DNA binding; metal ion binding; zinc ion binding