Recombinant Yeast Glutaredoxin 2, His-tagged

• Cat.No.: GRX2-76Y
• Product Overview: Recombinant cerevisiae Glutaredoxin-2 Saccharamyces conaining 6x His-tagged at C-terminus produced inE.Coliis a single, non-glycosylated, Polypeptide chain having a molecular mass of 17 kDa.

Specification

• Species: Yeast
• Source: E.coli
• Tag: His
• Description: GRX2 is a multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. Glutaredoxins are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions.
• Physical Appearance: Sterile Filtered clear colorless solution.
• Purity: Purity of GRX2 is greater than 90% as determined by SDS-PAGE.
• Formulation: Glutaredoxin-2 solution contains 25 mM Tris-HCl pH-7.5 & 0.01% Na Azide.
• Applications: ELISA, Western Blot, strongly binds to glutathione, reduced and oxidized.
• Stability: 1 week at 2-10°C. For long term store at -20 to -80°C.

Gene Information

• Gene Name: GRX2 Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress [ Saccharomyces cerevisiae ]
• Synonyms: TTR1; Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress; YDR513W; GRX2
• Gene ID: 852124
• Protein Refseq: NP_010801
• UniProt ID: GDBY
• Chromosome Location: IV