||Recombinant cerevisiae Glutaredoxin-2 Saccharamyces conaining 6x His-tagged at C-terminus produced inE.Coliis a single, non-glycosylated, Polypeptide chain having a molecular mass of 17 kDa.
||GRX2 is a multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. Glutaredoxins are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions.
||Sterile Filtered clear colorless solution.
||Purity of GRX2 is greater than 90% as determined by SDS-PAGE.
||Glutaredoxin-2 solution contains 25 mM Tris-HCl pH-7.5 & 0.01% Na Azide.
||ELISA, Western Blot, strongly binds to glutathione, reduced and oxidized.
||1 week at 2-10°C. For long term store at -20 to -80°C.