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Native Canine CASQ2

Cat.No. : CASQ2-30C
Product Overview : Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40--50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.
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  • Gene Information
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Source : Dog Heart
Species : Canine
Form : The protein was lyophilized from a concentrated solution (1mg/ml) containing 10mM Tris-HCl and 1mM EGTA.
Purity : Greater than 90% as determined by SDS-PAGE.
Usage : This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.
Storage : Lyophilized CASQ2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CASQ2 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Reconstitution : It is recommended to reconstitute the lyophilized CASQ2 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Gene Name : CASQ2?calsequestrin 2 (cardiac muscle) [?Canis lupus familiaris?(dog) ]
Official Symbol : CASQ2
Synonyms : CAL; CASQ2
Gene ID : 483134
mRNA Refseq : XM_540252
Protein Refseq : XP_540252
Chromosome Location : chromosome: 17
Function : calcium ion binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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