Native Canine CASQ2


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Native Canine CASQ2

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Cat.No. : CASQ2-30C
Product Overview : Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40--50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.
Source : Dog Heart
Species : Canine
Form : The protein was lyophilized from a concentrated solution (1mg/ml) containing 10mM Tris-HCl and 1mM EGTA.
Purity : Greater than 90% as determined by SDS-PAGE.
Usage : This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.
Storage : Lyophilized CASQ2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CASQ2 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Reconstitution : It is recommended to reconstitute the lyophilized CASQ2 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Gene Name : CASQ2?calsequestrin 2 (cardiac muscle) [?Canis lupus familiaris?(dog) ]
Official Symbol : CASQ2
Synonyms : CAL; CASQ2
Gene ID : 483134
mRNA Refseq : XM_540252
Protein Refseq : XP_540252
Chromosome Location : chromosome: 17
Function : calcium ion binding; protein binding

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