Native Human Bacterial/Permeability-Increasing Protein


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Native Human Bacterial/Permeability-Increasing Protein

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Cat.No. : BPI-182H
Description : Bacterial/Permeability-Increasing Protein (BPI) is present in the azurophilic granules of polymorphonuclear leukocytes (PMN). BPI is toxic only toward Gram-negative bacteria. This specificity is attributable to the strong attraction of BPI for the lipopolysaccharides (LPS) in the bacterial envelope. BPI is also an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis.
Source : Human Whole Blood
Species : Human
Form : Frozen
Molecular Mass : MW: 55,000
Purity : >95% by SDS-PAGE
Usage : For research use or for use in further manufacturing.
Quality Control Test : Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability : >1 year
Storage : <=>
Storage Buffer : 80 mM Citrate Phosphate, pH 5.6 , 0.75 M NaCl
Gene Name : BPI bactericidal/permeability-increasing protein [ Homo sapiens ]
Official Symbol : BPI
Synonyms : BPI; bactericidal/permeability-increasing protein; bactericidal permeability-increasing protein; BPI fold containing family D; member 1; BPIFD1; CAP 57; recombinant BPI holoprotein, rBPI; BPI fold containing family D, member 1; rBPI;
Gene ID : 671
mRNA Refseq : NM_001725
Protein Refseq : NP_001716
MIM : 109195
UniProt ID : P17213
Chromosome Location : 20q11.23
Function : Gram-negative bacterial cell surface binding; lipid binding; lipopolysaccharide binding;

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