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Active Native Human Cathepsin L

Cat.No. : CTSL-191H
  • Specification
  • Gene Information
  • Related Products
Description : The most powerful of the lysosomal proteases. It has a higher specific activity than cathepsin B and H in the degradation of a variety of physiological protein substrates. The level of cathepsin L is a strong predictor of relapse and survival following treatment of a primary breast tumor.
Source : Human Liver
Species : Human
Form : Frozen
Bio-activity : Greater than or equal to 0.5 U/mg. One unit is de ned as the amount of enzyme which hydrolyzes one umole of Z-Phe-Arg-AFC per minuteat 25°C in 400 mM Na acetate, pH 5.5 with 4 mM EDTA and 8 mM DTT.
Molecular Mass : 25,000-29,000
Usage : For research use or for use in further manufacturing.
Quality Control Test : Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability : >1 year
Storage : <=>
Storage Buffer : 20 mM malonate bu er, pH 5.5, with 1 mM EDTA, and 400 mM NaCl
Gene Name : CTSL cathepsin L [ Homo sapiens ]
Official Symbol : CTSL
Synonyms : MEP; CATL; CTSL1; cathepsin L1; major excreted protein
Gene ID : 1514
mRNA Refseq : NM_001257971
Protein Refseq : NP_001244900
MIM : 116880
UniProt ID : P07711
Chromosome Location : 9q21.33
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, conserved biosystem
Function : collagen binding; cysteine-type endopeptidase activity; cysteine-type peptidase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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