Recombinant Mouse Ctsl Protein (Thr18-Asn334), C-His tagged

• Cat.No.: Ctsl-5418M
• Product Overview: Recombinant mouse Ctsl (Thr18-Asn334) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: His
• Protein Length: Thr18-Asn334
• Description: This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the activation peptide and the cathepsin L1 heavy and light chains. The mature enzyme appears to be important in embryonic development through its processing of histone H3 and may play a role in disease progression in a model of kidney disease. Homozygous knockout mice for this gene exhibit hair loss, skin thickening, bone and heart defects, and enhanced susceptibility to bacterial infection. A pseudogene of this gene has been identified in the genome.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 34.87 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Ctsl cathepsin L [ Mus musculus (house mouse) ]
• Official Symbol: Ctsl
• Synonyms: Ctsl; cathepsin L; fs; MEP; nkt; CatL; Ctsl1; 1190035F06Rik; procathepsin L; Cat L; cathepsin L1; major excreted protein; p39 cysteine proteinase; EC 3.4.22.15
• Gene ID: 13039
• mRNA Refseq: NM_009984
• Protein Refseq: NP_034114
• UniProt ID: P06797