Native Human Immunoglobulin E (IgE)

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Native Human Immunoglobulin E (IgE)

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Cat.No. : IGHE-214H
Description : IgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior.
Source : Human Plasma
Species : Human
Form : Frozen
Molecular Mass : MW: 190,000
Purity : >=95% by SDS-PAGE.
Usage : For research use only.
Quality Control Test : Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability : >1 year
Storage : -20°C
Storage Buffer : 15 mM potassium phosphate, pH 7.4, with 150 mM NaCl and 0.05% NaN3.
Gene Name : IGHE Immunoglobulin heavy constant epsilon [ Homo sapiens ]
Official Symbol : IGHE
Synonyms : IGHE; Immunoglobulin heavy constant epsilon;
Gene ID : 3497
Chromosome Location : 14q32.33
Pathway : FCERI mediated Ca+2 mobilization, organism-specific biosystem; FCERI mediated NF-kB activation, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem
Function : antigen binding; contributes_to immunoglobulin receptor binding

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