Native Human Leucine-rich Alpha 2 Glycoprotein-1 (LRG1)

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Native Human Leucine-rich Alpha 2 Glycoprotein-1 (LRG1)

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Cat.No. : LRG1-240H
Description : LRG1 binds cytochrome c, an initiator/amplifier of programmed cell death (apoptosis), and by binding cytochrome c, is thought to play a role in cell survival. LRG1 is a biomarker associated with several cancers, including non-small cell lung cancer, colorectal cancer, and pancreatic cancer. Recent studies have shown it is three-fold more abundant in ovarian cancer serum compared to non-cancer control serum. LRG1 levels are only moderately correlated with CA125 levels.
Source : Human Plasma
Species : Human
Form : Lyophilized
Molecular Mass : 50,000 by SDS-PAGE
Purity : >= 95% by SDS-PAGE.
Applications : Positive reaction to anti-LRG1 on Western Blot
Usage : For research use only.
Quality Control Test : Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability : >1 year
Storage : <=>
Storage Buffer : 20 mM Tris, 20 mM NaCl, pH 7.5
Gene Name : LRG1 leucine-rich alpha-2-glycoprotein 1 [ Homo sapiens ]
Official Symbol : LRG1
Synonyms : LRG1; leucine-rich alpha-2-glycoprotein 1; leucine-rich alpha-2-glycoprotein; leucine rich alpha 2 glycoprotein; LRG; 1300008B03Rik; 2310031E04Rik; HMFT1766; FLJ45787;
Gene ID : 116844
mRNA Refseq : NM_052972
Protein Refseq : NP_443204
MIM : 611289
UniProt ID : P02750
Chromosome Location : 19
Function : molecular_function;

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