Native Bovine Factor IXa - EGR

PRODUCTS

Home / Products / Native Bovine Factor IXa - EGR

Native Bovine Factor IXa - EGR

Fixa Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : Fixa-279B
Description : Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid complex. The activation results from the cleavage of two peptide bonds in the factor IX molecule, releasing an activation glycopeptide with an apparent molecular weight of 10,000. The heavy chain of factor IXa (Mr=28,000) contains the serine protease catalytic domain, while the light chain (Mr=17,000) contains the membrane binding domain. Factor IXa functions as a serine protease involved in the activation of the zymogen, factor X, to form the enzyme, factor Xa. The factor IXa enzymatic activity is greatly enhanced by inclusion of its cofactor, factor VIIIa, in the presence of calcium ions on a phospholipid surface. Factor IXa is readily inhibited by antithrombin III, and this inhibition is greatly accelerated by the presence of heparin. Factor IXa is not inhibited by DFP.
Source : Plasma
Species : Bovine
Form : 20 mM Hepes, 150 mM NaCl, pH 7.4
Bio-activity : Factor IX clotting assay
Purity : >95% by SDS-PAGE. NOT tissue/cell culture grade. Not tested for endotoxin.
Characteristic : Extinction coefficient:14.0, Structure: 2 subunits, Mr=28,000 and 17,000 (5), NH2-terminal gla-domain, two EGF domains
Storage : -80°C

Online Inquiry


  •  
  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved.