"OTUD1" Related Products

Recombinant Human OTUD1, His-tagged

Cat.No.: OTUD1-128H
Product Overview: Recombinant Human OTUD1 CD(270-481), fused with N-terminal 6His, was expressed in E.coli.
Description: OTUD1 is a cysteine protease and is a member of the OTU superfamily of proteins (Balakirev et al., 2003). Cloning of the human gene was first described by Kayagaki et al. (2007).
Source: E. coli
Species: Human
Tag: His
Form: 50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol
Bio-activity: Deubiquitylase Enzyme Assay: The activity of His-OTUD1 was validated by determining the increase in fluorescence measured as a result of the enzyme catalysed cleavage of the fluorogenic substrate Ubiquitin-Rhodamine110-Glycine generating Ubiquitin and Rhodamine110-Glycine. Incubation of the substrate in the presence or absence of His-OTUD1 was compared confirming the deubiquitylating activity of His-OTUD1.
Molecular Mass: ~30kDa
Storage: 12 months at -70?C; aliquot as required.
Concentration: 0.5 mg/ml
Gene Name: OTUD1 OTU domain containing 1 [ Homo sapiens ]
Official Symbol: OTUD1
Synonyms: DUBA7; OTDC1
Gene ID: 220213
mRNA Refseq: NM_001145373.2
Protein Refseq: NP_001138845.1
MIM: 612022
UniProt ID: Q5VV17
Chromosome Location: 10p12.2

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