Recombinant Human ZNRF2, GST-tagged
| Cat.No. : |
ZNRF2-135H |
| Product Overview : |
Recombinant human ZNRF2 (amino acid residues 1-242), with N-terminal GST, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
| Description : |
The enzymes of the ubiquitylation pathway play a pivotal role in a number of cellular processes including the regulated and targeted proteasome-dependent degradation of substrate proteins. Three classes of enzymes are involved in the process of ubiquitylation; activating enzymes (E1s), conjugating enzymes (E2s) and protein ligases (E3s). Zinc and Ring Finger protein 2 (ZNRF2) is a member of the Really Interesting New Gene (RING) E3 protein ligase family and cloning of the human gene was first described by Araki et al. (2001). |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol |
| Molecular Mass : |
~50kDa |
| Storage : |
12 months at -70°C. Avoid multiple freeze/thaw cycles. |
| Concentration : |
0.5mg/ml |
| Gene Name : |
ZNRF2 zinc and ring finger 2 [ Homo sapiens ] |
| Official Symbol : |
ZNRF2 |
| Synonyms : |
ZNRF2; zinc and ring finger 2; E3 ubiquitin-protein ligase ZNRF2; RNF202; protein Ells2; RING finger protein 202; zinc finger/RING finger 2; zinc/RING finger protein 2; |
| Gene ID : |
223082 |
| mRNA Refseq : |
NM_147128 |
| Protein Refseq : |
NP_667339 |
| MIM : |
612061 |
| UniProt ID : |
Q8NHG8 |
| Chromosome Location : |
7p15.1 |
| Function : |
ligase activity; metal ion binding; zinc ion binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
