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Recombinant Chicken ANKMY2

Cat.No. : ANKMY2-2664C
Product Overview : Recombinant Chicken ANKMY2 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Chicken
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : ANKMY2 ankyrin repeat and MYND domain containing 2 [ Gallus gallus (chicken) ]
Official Symbol : ANKMY2
Gene ID : 420593
Protein Refseq : NP_001026150
UniProt ID : Q5ZMD2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (22)

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Are there any diseases associated with Ankmy2 protein mutations? 02/11/2023

Mutations in the Ankmy2 gene have been linked to certain neurological disorders, such as Gilles de la Tourette syndrome (GTS) and attention deficit hyperactivity disorder (ADHD). However, more research is needed to fully understand the role of Ankmy2 in these conditions.

What are the structural features of Ankmy2 protein? 08/21/2022

Ankmy2 protein consists of ankyrin repeat domains and a MYND domain. Ankyrin repeats are protein motifs involved in mediating protein-protein interactions, while the MYND domain is a zinc finger-like domain that is involved in DNA binding and transcriptional regulation.

Can Ankmy2 protein be targeted for therapeutic interventions? 05/28/2022

The potential for targeting Ankmy2 protein for therapeutic interventions is not well-established at this time. While mutations in the Ankmy2 gene have been associated with neurological disorders, the specific mechanisms by which these mutations contribute to disease pathology are still being elucidated. Once the precise role of Ankmy2 in these disorders is better understood, it may be possible to explore targeted therapeutic interventions. However, further research is needed before any specific therapeutic strategies can be developed.

How is Ankmy2 protein involved in protein-protein interactions? 12/18/2021

Ankmy2 contains ankyrin repeat domains, which are known to mediate protein-protein interactions. These repeats provide a structural framework that allows Ankmy2 to bind and interact with other proteins. By engaging in protein-protein interactions, Ankmy2 may participate in complex cellular processes, such as signaling cascades or protein assembly/disassembly.

Is Ankmy2 protein expressed in other tissues besides the brain? 12/07/2021

Yes, Ankmy2 protein is known to be expressed in several tissues besides the brain. It has been detected in various organs, including the heart, liver, kidney, lung, and skeletal muscle, suggesting potential roles for Ankmy2 outside of the central nervous system. However, the specific functions of Ankmy2 in these non-neuronal tissues are not yet well understood and require further investigation.

Has Ankmy2 been implicated in any developmental disorders or psychiatric conditions? 03/05/2021

Yes, Ankmy2 has been implicated in developmental disorders and psychiatric conditions. Mutations in the Ankmy2 gene have been identified in individuals with Gilles de la Tourette syndrome (GTS) and attention deficit hyperactivity disorder (ADHD). GTS is a neurodevelopmental disorder characterized by involuntary movements and vocalizations, while ADHD is a psychiatric disorder marked by inattention, hyperactivity, and impulsivity. However, the exact mechanisms by which Ankmy2 mutations contribute to these disorders are still being investigated.

How is Ankmy2 protein involved in transcriptional regulation? 08/11/2020

Ankmy2 contains a MYND domain, which is known to be involved in transcriptional regulation. This domain is capable of binding to DNA and interacting with other transcriptional regulators, suggesting that Ankmy2 may play a role in modulating gene expression. However, the specific target genes and transcriptional pathways regulated by Ankmy2 are still under investigation.

Are there any genetic variants in the Ankmy2 gene associated with other neurological disorders? 06/02/2020

While some studies have identified mutations in the Ankmy2 gene in individuals with Gilles de la Tourette syndrome and attention deficit hyperactivity disorder, there is currently limited evidence to suggest a direct association between Ankmy2 gene variants and other neurological disorders. However, with continued research and larger-scale genetic studies, it is possible that additional associations between Ankmy2 gene variants and other neurological disorders may be discovered.

Are there any known post-translational modifications of Ankmy2 protein? 02/13/2020

Currently, there is limited research on post-translational modifications of Ankmy2 protein. However, as post-translational modifications often play important roles in protein function and regulation, it is possible that Ankmy2 undergoes various modifications, such as phosphorylation, acetylation, or ubiquitination. Further research is needed to uncover these modifications and understand their impact on Ankmy2's activity.

What are the known interactions of Ankmy2 with other proteins? 11/26/2019

The known interactions of Ankmy2 with other proteins are currently limited. However, some studies have identified potential protein-protein interactions involving Ankmy2. For example, Ankmy2 has been found to interact with actin-binding proteins like filamin A and spectrin, suggesting a possible role in actin dynamics and cytoskeletal organization. Additionally, Ankmy2 has been shown to interact with other synaptic proteins like SAP102 and PSD-95, implicating its involvement in synapse formation and function. As research progresses, more interactions involving Ankmy2 may be discovered.

Can Ankmy2 protein interact with other proteins? 07/16/2019

Yes, Ankmy2 has been shown to interact with several proteins, including components of the nuclear pore complex and transcriptional regulators. These interactions suggest a role for Ankmy2 in regulating protein transport and gene expression.

What are the cellular and molecular functions of Ankmy2 protein? 04/23/2019

The cellular and molecular functions of Ankmy2 are still actively being investigated. However, some proposed functions include involvement in transcriptional regulation, protein-protein interactions, and potential roles in cellular processes like neuronal development, signaling, and synaptic function. Studies have also suggested a possible role for Ankmy2 in actin dynamics and cytoskeletal organization. Further research is needed to fully elucidate the breadth of Ankmy2's cellular and molecular functions.

What research is being conducted on Ankmy2 protein? 04/09/2019

Current research on Ankmy2 is focused on understanding its function and the molecular mechanisms underlying its involvement in neurological disorders. Scientists are also investigating potential therapeutic targets related to Ankmy2 for the treatment of these disorders.

Can Ankmy2 protein be targeted for drug development? 10/04/2018

Given its potential role in neurological disorders, Ankmy2 could be a potential target for drug development. However, further research is needed to fully elucidate its function and validate its therapeutic potential.

Can Ankmy2 protein be used as a biomarker for any diseases? 08/17/2018

Currently, there is no evidence to suggest that Ankmy2 protein can be used as a specific biomarker for any diseases. However, as our understanding of Ankmy2's functions and its involvement in various disorders improves, it may be possible to explore its potential as a biomarker in the future.

How is Ankmy2 protein involved in Gilles de la Tourette syndrome (GTS)? 06/30/2018

Mutations in the Ankmy2 gene have been identified in individuals with Gilles de la Tourette syndrome (GTS). These mutations may disrupt the normal function of the Ankmy2 protein, leading to abnormal neuronal activity and the manifestation of GTS symptoms. However, the exact mechanisms by which Ankmy2 mutations contribute to GTS are still being investigated.

Is there a specific cellular signaling pathway associated with Ankmy2 protein? 05/16/2018

The exact cellular signaling pathways regulated by Ankmy2 are not fully understood. However, studies have suggested that Ankmy2 may interact with proteins involved in Wnt signaling, a crucial pathway for development and tissue homeostasis. This suggests that Ankmy2 may have a role in modulating Wnt signaling, but further research is needed to clarify this relationship.

Are there any therapeutic strategies targeting Ankmy2 for the treatment of disorders? 03/04/2017

As of now, there are no known therapeutic strategies specifically targeting Ankmy2 for the treatment of disorders. However, ongoing research focusing on understanding the exact mechanisms by which Ankmy2 mutations contribute to diseases like Gilles de la Tourette syndrome and attention deficit hyperactivity disorder may provide insights into potential therapeutic approaches. Targeting Ankmy2 or related signaling pathways could potentially be explored as a future therapeutic strategy, but it is still in the early stages of discovery and development.

Are there any animal models or cell culture studies investigating the effects of Ankmy2 knockout or overexpression? 01/30/2017

As of now, there is limited information available on the effects of Ankmy2 knockout or overexpression in animal models or cell culture studies. Most research has focused on the identification of Ankmy2 mutations in individuals with neurodevelopmental disorders. However, with increasing interest in understanding the function of Ankmy2, it is conceivable that future studies will investigate the effects of Ankmy2 knockout or overexpression in various model systems to better understand its role in neurodevelopment and neuronal function.

Are there any other disorders or conditions associated with Ankmy2 protein? 01/05/2017

Besides Gilles de la Tourette syndrome, Ankmy2 has also been implicated in attention deficit hyperactivity disorder (ADHD). It is possible that Ankmy2 dysregulation or mutations may contribute to the development of ADHD symptoms and related cognitive impairments. Further research is needed to better understand the specific role of Ankmy2 in these disorders.

Is there any evidence linking Ankmy2 to actin dynamics or cytoskeletal organization? 11/17/2016

Yes, there is evidence suggesting a potential link between Ankmy2 and actin dynamics or cytoskeletal organization. Ankmy2 has been shown to interact with actin-binding proteins like filamin A and spectrin. Additionally, it has been implicated in processes like neurite outgrowth and axon guidance, which are regulated by the actin cytoskeleton. However, the precise mechanisms by which Ankmy2 influences actin dynamics or cytoskeletal organization are still unclear and require further investigation.

Are there any animal models or experimental studies investigating the role of Ankmy2 protein? 08/26/2016

several studies have examined the expression and function of Ankmy2 in various cell and animal models. For example, mouse models have been used to assess the impact of Ankmy2 mutations on neuronal development and behavior. Other experimental studies have investigated Ankmy2's role in cellular processes like neurite outgrowth and synaptic function using in vitro models. These studies contribute to our understanding of Ankmy2's potential role in neurodevelopmental disorders and neuronal function.

Customer Reviews (5)

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Reviews
05/04/2022

    In addition to its high-quality standards, the manufacturer of Ankmy2 protein offers excellent technical support.

    04/12/2020

      The Ankmy2 protein stands out for its exceptional quality, making it an excellent choice to meet my experimental requirements.

      01/27/2020

        This flexibility ensures that the Ankmy2 protein can address my specific research objectives efficiently.

        03/22/2018

          Its purity and consistency guarantee reliable and reproducible results, ensuring the reliability of my research outcomes.

          11/19/2017

            the Ankmy2 protein demonstrates outstanding performance in various experimental applications.

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