"CCL5" Related Products

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Recombinant Human chemokine (C-C motif) ligand 5, His-tagged

Cat. No. : CCL5-61H
Product Overview : Recombinant Human CCL5 comprises a 68 amino acid fragment (24-91) corresponding to the mature RANTES protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
Description : CCL5 (acronym for Regulated upon Activation, Normal T-cell Expressed, and presumably Secreted) is a member of the beta (CC) chemokine subfamily and is predominantly produced from T cells and platelets. RANTES has been shown to be a chemoattractant factor for monocytes, CD4+/CD45RO+ T lymphocytes and basophils. It has also been shown to induce the proliferation and activation of killer cells and may act as a HIV suppressive factor.
Source : E.coli.
Purity : >95% by SDS-PAGE
Form : Liquid
Storage : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
PDBrendering based on 1pmi. Available structures:1b3a,1eqt,1hrj,1rtn,1rto,1u4l,1u4m,1u4p,1u4r :

Gene Name : CCL5 chemokine (C-C motif) ligand 5 [ Homo sapiens ]
Synonyms : CCL5; D17S136E; MGC17164; RANTES; SCYA5; SISd; TCP228; chemokine (C-C motif) ligand 5; small inducible cytokine A5; SIS-delta; beta-chemokine RANTES; T-cell specific protein p288; T-cell specific RANTES protein; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys), member 5; regulated upon activation, normally T-expressed, and presumably secreted; CCL5; Chemokine (C-C motif) ligand 5; T-cell specific RANTES protein; T-cell; specific protein P288; beta chemokine RANTES precursor; SIS delta; EoCP; Eosinophil-chemotactic cytokine; T-cell specific RANTES protein; T-cell-specific protein RANTES; small inducible cytokine A5.
Gene ID : 6352
mRNA Refseq : NM_002985
Protein Refseq : NP_002976
MIM : 187011
UniProt ID : P13501
Chromosome Location : 17q11.2-q12
Pathway : Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Toll-like receptor signaling pathway; :Signaling by GPCR
Function : chemoattractant activity; chemokine activity; signal transducer activity

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