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Recombinant Human Cyclin-Dependent Kinases Regulatory Subunit 2, T7-Tagged

Cat. No.: CKS2-355H
Product Overview: Recombinant CKS2 fused with T7-tag was expressed in E.coli and purified by conventional chromatography techniques,11.3kDa (94aa),11.3kDa (94aa).
Description: Recombinant Human CKS2, also known as CDC28 Protein kinase 2 associates with the catalytic subunit of cyclin-dependent kinases and has therefore been assumed to play a direct role in cell cycle regulation. The function of CKS2 in somatic mammalian cells is not well understood although it is required for the first metaphase/anaphase transition during the meiosis. Emerging evidence shows that elevated expression of CKS2 protects the cells from apoptosis.
Source: Escherichia Coli.
Form: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 20% glycerol.
Purity: > 95% by SDS - PAGE.
Concentration: 1 mg/ml (determined by Bradford assay)
Sequences of amino acids: MASMTGGQQM GRGSHMAHKQ IYYSDKYFDE HYEYRHVMLP RELSKQVP KT HLMSEEEWRR LGVQQSLGWV HYMIHEPEPH ILLFRRPLPK DQQK
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: CKS2 CDC28 protein kinase regulatory subunit 2 [ Homo sapiens ]
Synonyms: CDC28 protein kinase 2; CKSHS2; Cyclin-dependent kinases regulatory subunit 2; CKS2; CDC28 protein kinase 2; CKS1(S. cerevisiae Cdc28/Cdc2 kinase subunit) homolog-2; CKS-2; CKSHS2; OTTHUMP00000021616; CDC28 protein kinase regulatory subunit 2.
Gene ID: 1164
mRNA Refseq: NM_001827
Protein Refseq: NP_001818
MIM: 116901
UniProt ID: P33552
Chromosome Location: 9q22
Function: Cyclin-dependent protein kinase regulator activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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