Recombinant Human Cellular Retinoic Acid Binding Protein 2

• Cat.No.: CRABP2-368H
• Product Overview: Recombinant human CRABP2 was expressed in E.coli and purified by using conventional chromatography techniques, 15.6 kDa (138 aa).

Specification

• Cat. No.: CRABP2-368H
• Description: The cellular retinoic acid-binding protein II (CRABP-II) is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus.
• Sequences of amino acids: MPNFSGNWKI IRSENFEELL KVLGVNVMLR KIAVAAASKP AVEIKQEGDT FYIKTSTTVR TTEINFKVGE EFEEQTVDGR PCKSLVKWES ENKMVCEQKL LKGEGPKTSW TRELTNDGEL ILTMTADDVV CTRVYVRE
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CRABP2 cellular retinoic acid binding protein 2 [ Homo sapiens ]
• Synonyms: CRABP-II; OTTHUMP00000038730; OTTHUMP00000038732; RBP6; Cellular retinoic acid-binding protein II; cellular retinoic acid binding protein 2; cellular retinoic acid-binding protein 2; CRABP2
• Gene ID: 1382
• mRNA Refseq: NM_001878
• Protein Refseq: NP_001869
• MIM: 180231
• UniProt ID: P29373
• Chromosome Location: 1q21.3
• Function: lipid binding; retinal binding; retinol binding; transporter activity