Recombinant Human KHK, MYC/DDK-tagged

• Cat.No.: KHK-492H
• Product Overview: Recombinant Human KHK, transcript variant b, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Molecular Mass: 32.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: KHK ketohexokinase (fructokinase) [ Homo sapiens (human) ]
• Official Symbol: KHK
• Synonyms: KHK; ketohexokinase (fructokinase); ketohexokinase; EC 2.7.1.3; ketohexokinase; Hepatic fructokinase
• Gene ID: 3795
• mRNA Refseq: NM_006488
• Protein Refseq: NP_006479
• MIM: 229800
• UniProt ID: P50053
• Chromosome Location: 2p23.3
• Pathway: Fructose and mannose metabolism; Metabolic pathways; Metabolism of carbohydrates
• Function: ATP binding; ketohexokinase activity