|Cat. No. :
|Product Overview :
||Recombinant humanGADD45G protein was expressed in E.coli and purified by using conventional chromatography techniques, 17.1 kDa (159 aa).
||GADD45G is a member of GADD45 family (GADD45α, β, and γ) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents.
||Liquid. In 20 mM Tris-HCl buffer (pH 7.5).
||> 95% by SDS - PAGE.
||1 mg/ml (determined by Bradford assay)
|Sequences of amino acids :
||MTLEEVRGQD TVPESTARMQ GAGKALHELL LSAQRQGCLT AGVYESAKVL NVDPDNVTFC VLAAGEEDEG DIALQIHFTL IQAFCCENDI DIVRVGD VQ R LAAIVGAGEE AGAPGDLHCI LISNPNEDAW KDPALEKLSL FCEESRSVND WVPSITLPE
||Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.