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Recombinant Human Growth Arrest and DNA-damage-Inducible, Gamma

Cat.No. : GADD45G-359H
Product Overview : Recombinant humanGADD45G protein was expressed in E.coli and purified by using conventional chromatography techniques, 17.1 kDa (159 aa).
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Cat. No. : GADD45G-359H
Description : GADD45G is a member of GADD45 family (GADD45α, β, and γ) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents.
Source : Escherichia Coli.
Form : Liquid. In 20 mM Tris-HCl buffer (pH 7.5).
Purity : > 95% by SDS - PAGE.
Concentration : 1 mg/ml (determined by Bradford assay)
Sequences of amino acids : MTLEEVRGQD TVPESTARMQ GAGKALHELL LSAQRQGCLT AGVYESAKVL NVDPDNVTFC VLAAGEEDEG DIALQIHFTL IQAFCCENDI DIVRVGD VQ R LAAIVGAGEE AGAPGDLHCI LISNPNEDAW KDPALEKLSL FCEESRSVND WVPSITLPE
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : GADD45G growth arrest and DNA-damage-inducible, gamma [ Homo sapiens ]
Synonyms : growth arrest and DNA-damage-inducible, gamma; GADD45-gamma; OTTHUMP00000021623; gadd-related protein, 17 kD; GADD45G; DDIT2; GADD45gamma; CR6; GRP17; DDIT-2; Cytokine-responsive protein CR6; DNA-damage-inducible transcript 2.
Gene ID : 10912
mRNA Refseq : NM_006705
Protein Refseq : NP_006696
MIM : 604949
UniProt ID : O95257
Chromosome Location : 9q22.1-q22.2
Function : protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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