Recombinant Human Growth Arrest and DNA-damage-Inducible, Gamma GADD45G-359H

Recombinant Human Growth Arrest and DNA-damage-Inducible, Gamma

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Recombinant Human Growth Arrest and DNA-damage-Inducible, Gamma

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Cat. No. : GADD45G-359H
Product Overview : Recombinant humanGADD45G protein was expressed in E.coli and purified by using conventional chromatography techniques, 17.1 kDa (159 aa).
Description : GADD45G is a member of GADD45 family (GADD45α, β, and γ) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents.
Source : Escherichia Coli.
Form : Liquid. In 20 mM Tris-HCl buffer (pH 7.5).
Purity : > 95% by SDS - PAGE.
Concentration : 1 mg/ml (determined by Bradford assay)
Sequences of amino acids : MTLEEVRGQD TVPESTARMQ GAGKALHELL LSAQRQGCLT AGVYESAKVL NVDPDNVTFC VLAAGEEDEG DIALQIHFTL IQAFCCENDI DIVRVGD VQ R LAAIVGAGEE AGAPGDLHCI LISNPNEDAW KDPALEKLSL FCEESRSVND WVPSITLPE
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : GADD45G growth arrest and DNA-damage-inducible, gamma [ Homo sapiens ]
Synonyms : growth arrest and DNA-damage-inducible, gamma; GADD45-gamma; OTTHUMP00000021623; gadd-related protein, 17 kD; GADD45G; DDIT2; GADD45gamma; CR6; GRP17; DDIT-2; Cytokine-responsive protein CR6; DNA-damage-inducible transcript 2.
Gene ID : 10912
mRNA Refseq : NM_006705
Protein Refseq : NP_006696
MIM : 604949
UniProt ID : O95257
Chromosome Location : 9q22.1-q22.2
Function : protein binding

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