Recombinant Human Heat Shock Factor Binding Protein 1 HSBP1-311H

Recombinant Human Heat Shock Factor Binding Protein 1

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Recombinant Human Heat Shock Factor Binding Protein 1

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Cat. No. : HSBP1-311H
Product Overview : Recombinant Human HSBP1 protein was overexpressed in E.coli and purified to apparent homogeneity by using conventional column chromatography techniques (76 aa, 8.5 kDa).
Description : Heat shock factor binding protein 1 (HSBP1) is a 76 amino acid protein that binds to heat shock factor 1(HSF1), which is a transcription factor involved in the HS response. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulated HSF1 DNA-binding activity.
Source : E.coli.
Formulation : Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT, 50 mM NaCl, 20% glycerol.
Molecular Weight : 8.5 kDa (76aa).
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequence : MAETDPKTVQ DLTSVVQTLL QQMQDKFQTM SDQIIGRIDD MSSRIDDLEK NIADLMTQAG VEELESENKI PATQKS
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : HSBP1
Synonyms : HSBP1; heat shock factor binding protein 1; NPC-A-13; DKFZp686D1664; DKFZp686O24200; HSF1BP; Nasopharyngeal carcinoma-associated antigen 13.
Gene ID : 3281
mRNA Refseq : NM_001537.2
Protein Refseq : NP_001528.1
MIM : 604553
UniProt ID : O75506
Chromosome Location : 16q23.3
Function : transcription corepressor activity.

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