Recombinant Zebrafish SMO
Cat.No. : | SMO-8656Z |
Product Overview : | Recombinant Zebrafish SMO full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | smo smoothened, frizzled class receptor [ Danio rerio (zebrafish) ] |
Official Symbol : | SMO |
Gene ID : | 30225 |
mRNA Refseq : | NM_131027 |
Protein Refseq : | NP_571102 |
UniProt ID : | Q90X26 |
Products Types
◆ Recombinant Protein | ||
SMO-28H | Recombinant Human SMO Protein | +Inquiry |
SMO-8486M | Recombinant Mouse SMO Protein, His (Fc)-Avi-tagged | +Inquiry |
SMO-2707H | Recombinant Human SMO Protein, His-tagged | +Inquiry |
SMO-4097H | Recombinant Human SMO Protein, His (Fc)-Avi-tagged | +Inquiry |
SMO-5282R | Recombinant Rat SMO Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionAberrant activation of the SMO protein is associated with several types of cancer, including basal cell carcinoma and medulloblastoma. Mutations or overexpression of SMO can lead to uncontrolled cell growth and tumorigenesis.
Yes, researchers are actively investigating the role of SMO protein in various diseases beyond cancer, including neurological disorders and regenerative medicine.
SMO protein modulation can influence stem cell fate decisions, playing a role in processes such as self-renewal and differentiation.
SMO inhibitors are being explored as therapeutic agents in cancer treatment, particularly for tumors driven by abnormal Hedgehog signaling. These inhibitors aim to block the activity of SMO and, consequently, disrupt the downstream signaling cascade.
Clinical trials have shown promise for SMO inhibitors in treating basal cell carcinoma, medulloblastoma, and other cancers with dysregulated Hedgehog signaling.
Customer Reviews (3)
Write a reviewThe manufacturer of SMO protein plays a crucial role in supporting my research endeavors.
The use of SMO protein in my research offers significant advantages in detecting cell death processes and investigating coagulation and thrombosis mechanisms.
Its ability to bind to negatively charged phospholipids, particularly during blood clot formation, has made it invaluable for in vitro and in vivo investigations of hemostatic mechanisms.
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